Opportunity Information: Apply for PAR 19 266
The Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models funding opportunity (PAR-19-266) is a National Institutes of Health (NIH) grant program aimed specifically at small business-led development projects under the Small Business Technology Transfer (STTR) mechanism. It supports early-stage, commercialization-oriented research and development that results in practical, usable tools or devices for animal research environments. The overall focus is not on funding animal studies for their own sake, but on creating new technologies that make animal care, handling, and facility operations better, safer, more efficient, and more supportive of high-quality biomedical and bio-behavioral research.
This FOA invites proposals to design, build, and test novel tools and devices that directly improve the welfare of laboratory animals and the daily realities of running animal research facilities. In plain terms, it is looking for innovations that reduce stress and risk during animal handling, streamline routine husbandry and facility management tasks, and strengthen the reliability and quality of experiments that depend on animal models. The opportunity also highlights improvements to facility infrastructure and environmental conditions, meaning it is open to technologies that help maintain or monitor parameters like housing conditions, sanitation, airflow, temperature, humidity, noise, lighting cycles, enrichment, or other environmental factors that can influence both animal well-being and experimental reproducibility.
The funding mechanism is STTR, which is distinct from SBIR in that it requires a formal collaborative relationship between an eligible small business concern and a nonprofit research institution (such as a university, medical center, or research institute). The intent of using STTR here is to encourage technology transfer: pairing the product-development and commercialization capacity of a small business with the scientific or engineering expertise and facilities of a research institution. The award types referenced, R41 and R42, correspond to the typical STTR phased structure (Phase I and Phase II), where Phase I generally supports feasibility and proof-of-concept work and Phase II supports more advanced development and validation toward a market-ready product.
The announcement is explicitly labeled "Clinical Trial Not Allowed," which means the proposed work cannot include clinical trials as defined by NIH. This lines up with the purpose of the program: it is centered on tools and devices for animal research facilities and animal model support, rather than interventions tested in human participants. Applicants should still expect to follow NIH rules around animal welfare, ethical use, and oversight where animal testing or validation is involved, but the FOA is not designed for human clinical evaluation.
Eligibility is limited to small businesses. Foreign organizations are not eligible to apply as the primary applicant: non-U.S. entities (foreign institutions) cannot apply, and non-U.S. components of U.S. organizations are also not eligible to apply as components. However, the FOA notes that "foreign components" may be allowed as defined in NIH policy, which typically refers to discrete project elements performed outside the United States under a U.S. applicant award, subject to NIH review and approval. In practice, that means the applying organization must be a U.S. small business, but certain justified international collaborations or activities could be permissible if they meet NIH requirements.
In terms of administrative details, the opportunity is categorized as discretionary funding and uses the grant funding instrument. It falls under the NIH funding activity category of health and is associated with CFDA number 93.351. The opportunity was created on 2019-05-02, and the original closing date listed in the provided data is 2021-04-05. The source data does not specify an award ceiling or the expected number of awards, so applicants would typically need to consult the full FOA text and any associated NIH institute/center guidance for budget expectations, project period norms, and programmatic priorities.
Overall, this FOA is best understood as a targeted NIH technology-development program for small businesses that can deliver tangible, facility-ready innovations supporting animal care and animal-model-based research. Successful projects are likely to be those that solve clear operational or welfare problems in animal facilities, demonstrate a credible path to adoption by research institutions, and align with the practical constraints of animal care programs (ease of use, durability, cleanliness, compliance, scalability, and measurable benefits to animal well-being and research quality).Apply for PAR 19 266
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351.
- This funding opportunity was created on 2019-05-02.
- Applicants must submit their applications by 2021-04-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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FAQs: Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (PAR-19-266)
What is PAR-19-266?
PAR-19-266 is a National Institutes of Health (NIH) funding opportunity titled "Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models." It supports small business-led projects to develop practical tools or devices used in animal research facilities and in the care and support of animal models.
What is the main goal of this funding opportunity?
The goal is to support early-stage, commercialization-oriented research and development that produces usable technologies for animal research environments. The emphasis is on creating new tools and devices that improve animal welfare and make facility operations better, safer, and more efficient, while also supporting high-quality and reproducible biomedical and bio-behavioral research.
Is this grant meant to fund animal studies themselves?
No. The overall focus is not on funding animal studies for their own sake. It is focused on developing technologies (tools and devices) that improve animal care, handling, and facility operations. Any animal work would be in service of designing, building, testing, or validating the tool or device.
What types of projects are encouraged?
Projects are encouraged that design, build, and test novel tools and devices that directly improve the welfare of laboratory animals and the day-to-day operations of animal research facilities. The program is looking for innovations that reduce stress and risk during handling, streamline routine husbandry and facility management tasks, and improve the reliability and quality of experiments that depend on animal models.
What kinds of facility or environmental improvements fit this program?
The opportunity highlights improvements to facility infrastructure and environmental conditions. This includes technologies that help maintain or monitor parameters such as housing conditions, sanitation, airflow, temperature, humidity, noise, lighting cycles, enrichment, and other environmental factors that can influence animal well-being and experimental reproducibility.
What funding mechanism does this opportunity use?
This opportunity uses the Small Business Technology Transfer (STTR) mechanism. STTR is designed to support technology transfer by pairing a small business with a nonprofit research institution in a formal collaboration.
How is STTR different from SBIR for this opportunity?
STTR requires a formal collaborative relationship between an eligible small business concern and a nonprofit research institution (for example, a university, medical center, or research institute). The intent is to combine the product-development and commercialization capacity of the small business with the scientific or engineering expertise and facilities of the research institution.
What award types are associated with PAR-19-266?
The award types referenced are R41 and R42, which correspond to the typical STTR phased structure: Phase I (R41) and Phase II (R42).
What is the difference between Phase I (R41) and Phase II (R42) under STTR?
Phase I (R41) generally supports feasibility and proof-of-concept work. Phase II (R42) generally supports more advanced development and validation toward a market-ready product.
Are clinical trials allowed under this opportunity?
No. The announcement is explicitly labeled "Clinical Trial Not Allowed." The proposed work cannot include clinical trials as defined by NIH.
Why are clinical trials not allowed?
The program is centered on tools and devices for animal research facilities and animal model support, rather than interventions tested in human participants. It is intended for technology development in animal research environments, not human clinical evaluation.
Does "Clinical Trial Not Allowed" mean no oversight is required?
No. Even though human clinical trials are not allowed, applicants should still expect to follow NIH rules related to animal welfare, ethical use, and oversight where animal testing or validation is involved.
Who is eligible to apply?
Eligibility is limited to small businesses. The applying organization must be an eligible small business concern.
Can a university or nonprofit apply as the lead applicant?
No. This is an STTR opportunity that is small business-led. A nonprofit research institution participates as a required collaborator, but the primary applicant is a small business.
Are foreign organizations eligible to apply?
No. Foreign organizations are not eligible to apply as the primary applicant. Non-U.S. entities cannot apply, and non-U.S. components of U.S. organizations are also not eligible to apply as components.
Are any international activities allowed at all?
The opportunity notes that "foreign components" may be allowed as defined in NIH policy. In practical terms, the applicant must be a U.S. small business, but certain justified project elements performed outside the United States could be permissible if they meet NIH requirements and receive NIH review and approval.
What is the role of the nonprofit research institution in an STTR application?
The nonprofit research institution is a formal collaborator intended to provide scientific or engineering expertise and access to facilities, supporting technology development and helping move innovations toward practical use and commercialization.
What makes a project a strong fit for this FOA?
Projects are likely to be competitive when they solve clear operational or welfare problems in animal facilities, produce tangible facility-ready innovations, and show a credible path to adoption by research institutions. Alignment with practical constraints in animal care programs is emphasized, such as ease of use, durability, cleanliness, compliance, scalability, and measurable benefits to animal well-being and research quality.
What kind of end product is NIH looking for?
The program is oriented toward practical, usable tools or devices that can be used in animal research environments. The emphasis is on deliverable technologies that can be adopted in real facilities and that support commercialization goals typical of STTR.
What is the funding instrument and funding type?
The opportunity uses the grant funding instrument and is categorized as discretionary funding.
What is the NIH activity category for this opportunity?
It falls under the NIH funding activity category of health.
What CFDA number is associated with this opportunity?
The associated CFDA number is 93.351.
When was this opportunity created?
The opportunity was created on 2019-05-02.
What is the closing date listed in the provided information?
The original closing date listed in the provided data is 2021-04-05.
Is there an award ceiling or expected number of awards listed here?
No. The provided information does not specify an award ceiling or the expected number of awards.
How should applicants approach budgets and project periods if those details are not listed here?
Because award ceiling, number of awards, and other budget expectations are not included in the provided data, applicants would typically consult the full FOA text and any associated NIH institute/center guidance for budget expectations, project period norms, and programmatic priorities.
What is the program primarily trying to improve in animal research settings?
The program targets improvements in animal welfare, safe and low-stress handling, efficient husbandry and facility operations, and environmental management that supports reproducible research outcomes.
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