Opportunity Information: Apply for RFA CA 19 025
The grant opportunity "Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional)" (RFA-CA-19-025) is a National Cancer Institute (NCI) funding announcement under the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH). It uses a cooperative agreement mechanism, meaning awardees can expect substantial scientific or programmatic involvement from NCI compared with a standard research grant. It is specifically designed for revision applications to already-active NCI U54 Resource-Related Research Projects. In other words, this is not meant for brand-new U54 proposals; it is aimed at teams that already have an NCI-funded U54 and want to revise and expand that funded project in a targeted way.
The main goal is to speed up cancer research progress by encouraging existing U54 projects to incorporate a novel technology or technical approach that was developed with support from NCI's Innovative Molecular Analysis Technologies (IMAT) program. The FOA is focused on taking a promising IMAT-supported tool, method, or instrument and integrating it into a real-world, resource-oriented research setting where it can be tested, validated independently, and positioned for broader use. The emphasis is on accelerating the parent U54 project's progress by either expanding the original scientific questions or enabling the project to reach its goals faster or more effectively through this new technology insertion.
A central theme of the opportunity is independent validation and readiness for the wider research community. Rather than simply adopting a new tool, awardees are expected to help demonstrate that an emerging IMAT technology is suitable and reliable for the intended user community, which can include cancer researchers, technology users, or other stakeholders tied to the U54 resource mission. This reflects a translational technology-development mindset: moving innovations from earlier development stages into settings where performance, reproducibility, usability, and fit-for-purpose can be demonstrated in a credible, independent way.
The announcement also ties into IMAT's broader purpose of promoting interdisciplinary collaboration. By encouraging U54 teams to bring in IMAT-born technologies, the FOA supports cross-cutting partnerships between technology developers and domain experts who can stress-test tools against real cancer research needs. The expectation is that this kind of collaboration will lead to more innovative and practical methods that ultimately enable scientific discovery and accelerate cancer research, particularly by improving how molecular analyses are performed or interpreted.
From an administrative and funding standpoint, the opportunity is categorized as discretionary funding and sits within the Education and Health activity category, with CFDA number 93.394. The award ceiling listed is $150,000, and the NCI anticipated making about three awards. The creation date for the opportunity is January 7, 2019, and the original closing date was September 27, 2019, indicating it was a time-limited solicitation during that period.
Eligibility is broad and includes many common research-performing and public-serving entities. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as specified); for-profit organizations other than small businesses; and small businesses. The listing also includes an "Others" category with additional eligibility clarifications referenced in the full FOA text, which typically covers special cases or additional organizational types allowed by NIH policy or the specific program design.
The "Clinical Trials Optional" designation indicates that, depending on the scope of the proposed revision, clinical trial activity may be permitted but is not required. Practically, this signals flexibility: projects can be purely resource/tool integration and validation in preclinical or research settings, or they can include clinical trial components if those are appropriate and consistent with NIH definitions and the parent U54's scope. The core requirement remains that the application is a revision to an existing NCI U54 Resource-Related Research Project and that the revision meaningfully incorporates an IMAT-supported technology to advance or accelerate the parent project's cancer research objectives.Apply for RFA CA 19 025
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394.
- This funding opportunity was created on Jan 07, 2019.
- Applicants must submit their applications by Sep 27, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Browse more opportunities from the same agency: Department of Health and Human Services, National Institutes of Health
Browse more opportunities from the same category: Education, Health
Next opportunity: Localworks Pre-Award Survey Option
Previous opportunity: Process Scale-Up and Optimization/Efficiency Improvements for Rare Earth Elements (REE) and Critical Materials (CM) Recovery from Coal-Based Resources
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA CA 19 025
Applicants also applied for:
Applicants who have applied for this opportunity (RFA CA 19 025) also looked into and applied for these:
| Funding Opportunity |
|---|
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P01 Clinical Trial Optional) Apply for RFA CA 19 026 Funding Number: RFA CA 19 026 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional) Apply for RFA CA 19 023 Funding Number: RFA CA 19 023 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI- Supported Technology to Accelerate Cancer Research (U01 Clinical Trial Optional) Apply for RFA CA 19 024 Funding Number: RFA CA 19 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Distance Learning and Telemedicine Grants. Apply for RUS 19 02 DLT Funding Number: RUS 19 02 DLT Agency: Department of Agriculture, Utilities Programs Category: Education, Health Funding Amount: $500,000 |
| Distance Learning and Telemedicine Grants--Opioid. Apply for RUS 19 01 DLT Funding Number: RUS 19 01 DLT Agency: Department of Agriculture, Utilities Programs Category: Education, Health Funding Amount: $500,000 |
| Feasibility and Planning Studies for Development of Specialized Programs of Research Excellence (SPOREs) to Investigate Cancer Health Disparities (P20 Clinical Trial Optional) Apply for RFA CA 19 034 Funding Number: RFA CA 19 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $800,000 |
| Optimizing the Management and Outcomes for Cancer Survivors Transitioning to Follow-up Care (R01 Clinical Trial Required) Apply for RFA CA 19 035 Funding Number: RFA CA 19 035 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| American Schools and Hospitals Abroad Program Worldwide Apply for 72ASHA19RFA00001 Funding Number: 72ASHA19RFA00001 Agency: Agency for International Development Category: Education, Health Funding Amount: $2,000,000 |
| Revision Applications to Support the Application of Informatics Technology for Cancer Research (R01 Clinical Trials Optional) Apply for RFA CA 19 062 Funding Number: RFA CA 19 062 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| Revision Applications to Support the Application of Informatics Technology for Cancer Research (U01 Clinical Trials Optional) Apply for RFA CA 19 061 Funding Number: RFA CA 19 061 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| Revision Applications to Support the Application of Informatics Technology for Cancer Research (U24 Clinical Trials Optional) Apply for RFA CA 19 063 Funding Number: RFA CA 19 063 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| The National Drug Abuse Treatment Clinical Trials Network (UG1 Clinical Trial Required) Apply for RFA DA 20 024 Funding Number: RFA DA 20 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Limited Competition: Pediatric Brain Tumor Consortium (UM1 Clinical Trials Required) Apply for RFA CA 19 059 Funding Number: RFA CA 19 059 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $3,300,000 |
| Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Coordination, Analysis, and Scientific Outreach (UM1 Clinical Trial Not Allowed) Apply for RFA DA 20 027 Funding Number: RFA DA 20 027 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network (NCTN)(U24 Clinical Trial Not Allowed) Apply for RFA CA 20 002 Funding Number: RFA CA 20 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $3,000,000 |
| Communication and Decision Making for Individuals with Inherited Cancer Syndromes (U01 Clinical Trial Optional) Apply for RFA CA 20 006 Funding Number: RFA CA 20 006 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $600,000 |
| Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R21 Clinical Trials Not Allowed) Apply for RFA CA 20 017 Funding Number: RFA CA 20 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trials Not Allowed) Apply for RFA CA 20 020 Funding Number: RFA CA 20 020 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R21 Clinical Trials Not Allowed) Apply for RFA CA 20 019 Funding Number: RFA CA 20 019 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trials Not Allowed) Apply for RFA CA 20 018 Funding Number: RFA CA 20 018 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA CA 19 025", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.