Opportunity Information: Apply for CDC RFA GH16 1602

This grant opportunity, titled "Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling" (Funding Opportunity Number: CDC RFA GH16-1602), is a CDC cooperative agreement focused on using advanced, integrated modeling to support global decision-making as the world moves through the polio "endgame" phase. The work centers on applying a dynamic global model that simulates polio transmission and the impact of interventions while also accounting for associated risks and costs. The purpose is to generate practical evidence that can help global partners make timely and defensible policy choices in a period where program decisions become more complex and the consequences of missteps can be significant.

A key feature of the opportunity is that it leverages a specific modeling capability developed by Kid Risk, Inc., described as the only available integrated dynamic global model that combines infection dynamics with intervention strategies and their downstream cost and risk implications. The model is presented as the product of roughly 12 years of iterative development, including extensive literature review, data collection, and refinement through collaboration with major polio stakeholders such as CDC, WHO, and other international experts. That history matters to the opportunity because it implies the work is not starting from scratch; instead, it builds on a mature modeling platform and a deep, curated evidence base about outbreaks, policies, operational risks, and program costs.

The intended outputs are analyses and decision-support materials that inform the Global Polio Eradication Initiative (GPEI) partners, the Strategic Advisory Group of Experts on Immunization (SAGE), and individual countries. In practical terms, the work is meant to translate complex global data into actionable insights that can guide policy formulation and implementation, particularly around endgame strategies such as managing outbreak risk, selecting immunization approaches, and planning for oral polio vaccine (OPV) cessation. Because OPV cessation involves balancing the benefits of stopping OPV use against the risks of vaccine-derived poliovirus emergence and potential outbreaks, the grant emphasizes the need for rigorous, integrated assessments that include epidemiology, strategy options, and resource implications.

Another emphasized deliverable is a proposed surveillance decision support tool designed to help GPEI and countries use resources more carefully and strategically. This tool would support decisions tied to surveillance intensity and design, vaccination policy choices, and planning timelines, with the broader aim of improving program efficiency while protecting gains toward eradication. The decision-support focus signals that the expected value is not just academic modeling, but usable guidance that can be incorporated into real-world planning and policy discussions.

Administratively, this is a discretionary funding opportunity under a cooperative agreement mechanism, meaning CDC would likely expect substantial involvement in shaping the work, reviewing outputs, and aligning analyses with program needs. It is categorized under health activity (CFDA 93.318), with eligibility listed as "Others." The opportunity anticipated a single award (Expected Awards: 1). The posting indicates an original closing date of 2016-12-30 and a creation date of 2015-11-18. The listed award ceiling is shown as 0 in the source text, which typically suggests that the ceiling amount was not specified in the extract provided rather than implying no funding, but the summary as published does not state a maximum award amount.

Overall, the opportunity is designed to strengthen global polio eradication planning by using a highly specialized, integrated modeling approach to answer policy-relevant questions and to provide tools that help decision-makers weigh tradeoffs among intervention options, risks, and costs as the eradication initiative approaches the final and most operationally sensitive stages.

  • The Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
  • This funding opportunity was created on 2015-11-18.
  • Applicants must submit their applications by 2016-12-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others.
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