Opportunity Information: Apply for CDC RFA GH16 1602
This grant opportunity, titled "Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling" (Funding Opportunity Number: CDC RFA GH16-1602), is a CDC cooperative agreement focused on using advanced, integrated modeling to support global decision-making as the world moves through the polio "endgame" phase. The work centers on applying a dynamic global model that simulates polio transmission and the impact of interventions while also accounting for associated risks and costs. The purpose is to generate practical evidence that can help global partners make timely and defensible policy choices in a period where program decisions become more complex and the consequences of missteps can be significant.
A key feature of the opportunity is that it leverages a specific modeling capability developed by Kid Risk, Inc., described as the only available integrated dynamic global model that combines infection dynamics with intervention strategies and their downstream cost and risk implications. The model is presented as the product of roughly 12 years of iterative development, including extensive literature review, data collection, and refinement through collaboration with major polio stakeholders such as CDC, WHO, and other international experts. That history matters to the opportunity because it implies the work is not starting from scratch; instead, it builds on a mature modeling platform and a deep, curated evidence base about outbreaks, policies, operational risks, and program costs.
The intended outputs are analyses and decision-support materials that inform the Global Polio Eradication Initiative (GPEI) partners, the Strategic Advisory Group of Experts on Immunization (SAGE), and individual countries. In practical terms, the work is meant to translate complex global data into actionable insights that can guide policy formulation and implementation, particularly around endgame strategies such as managing outbreak risk, selecting immunization approaches, and planning for oral polio vaccine (OPV) cessation. Because OPV cessation involves balancing the benefits of stopping OPV use against the risks of vaccine-derived poliovirus emergence and potential outbreaks, the grant emphasizes the need for rigorous, integrated assessments that include epidemiology, strategy options, and resource implications.
Another emphasized deliverable is a proposed surveillance decision support tool designed to help GPEI and countries use resources more carefully and strategically. This tool would support decisions tied to surveillance intensity and design, vaccination policy choices, and planning timelines, with the broader aim of improving program efficiency while protecting gains toward eradication. The decision-support focus signals that the expected value is not just academic modeling, but usable guidance that can be incorporated into real-world planning and policy discussions.
Administratively, this is a discretionary funding opportunity under a cooperative agreement mechanism, meaning CDC would likely expect substantial involvement in shaping the work, reviewing outputs, and aligning analyses with program needs. It is categorized under health activity (CFDA 93.318), with eligibility listed as "Others." The opportunity anticipated a single award (Expected Awards: 1). The posting indicates an original closing date of 2016-12-30 and a creation date of 2015-11-18. The listed award ceiling is shown as 0 in the source text, which typically suggests that the ceiling amount was not specified in the extract provided rather than implying no funding, but the summary as published does not state a maximum award amount.
Overall, the opportunity is designed to strengthen global polio eradication planning by using a highly specialized, integrated modeling approach to answer policy-relevant questions and to provide tools that help decision-makers weigh tradeoffs among intervention options, risks, and costs as the eradication initiative approaches the final and most operationally sensitive stages.Apply for CDC RFA GH16 1602
- The Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
- This funding opportunity was created on 2015-11-18.
- Applicants must submit their applications by 2016-12-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others.
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Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The opportunity is titled "Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling."
What is the Funding Opportunity Number?
The Funding Opportunity Number is CDC RFA GH16-1602.
Which agency is offering this opportunity?
This opportunity is offered by the Centers for Disease Control and Prevention (CDC).
What type of funding mechanism is being used?
The opportunity is a CDC cooperative agreement. This structure typically means CDC expects substantial involvement in the work, such as helping align analyses to program needs, reviewing outputs, and coordinating with partners.
Is this a discretionary grant opportunity?
Yes. The opportunity is described as a discretionary funding opportunity under a cooperative agreement mechanism.
What is the main purpose of this cooperative agreement?
The purpose is to support global decision-making during the polio "endgame" by applying advanced, integrated modeling. The modeling is intended to produce practical evidence to help global partners make timely, defensible policy choices at a stage where decisions are more complex and the consequences of errors can be significant.
What does "integrated modeling" mean in the context of this opportunity?
In this opportunity, integrated modeling refers to using a dynamic global model that simulates polio transmission and the impact of interventions, while also accounting for related risks and costs. The goal is to evaluate strategy options in a way that connects epidemiology, operational realities, and resource implications.
What phase of polio eradication does the work focus on?
The work focuses on the polio "endgame" phase, when eradication efforts are nearing completion and policy and operational decisions become particularly sensitive and high-stakes.
Why is the endgame phase described as more complex?
Because the final stages of eradication involve tighter tradeoffs and higher consequences for missteps. Decisions may need to balance outbreak risk, vaccination strategies, surveillance choices, and costs, often under uncertainty.
What specific modeling capability is highlighted in the opportunity?
The opportunity highlights a specific integrated dynamic global model developed by Kid Risk, Inc., described as the only available model that combines infection dynamics with intervention strategies and downstream cost and risk implications.
Why does the opportunity emphasize the Kid Risk, Inc. model?
The opportunity emphasizes it because it is presented as a mature platform built over roughly 12 years, supported by extensive literature review, data collection, and iterative refinement with major polio stakeholders. This suggests analyses would build on an established model rather than starting from scratch.
How long has the model reportedly been in development?
The model is described as the product of about 12 years of iterative development.
Who has been involved in refining or informing the model?
The description notes collaboration and refinement through engagement with major polio stakeholders and experts, including CDC, WHO, and other international experts.
Who are the intended users of the outputs from this work?
The intended outputs are meant to inform GPEI partners, the Strategic Advisory Group of Experts on Immunization (SAGE), and individual countries.
What kinds of outputs are expected?
The opportunity describes expected outputs as analyses and decision-support materials that translate complex global data into actionable insights for policy formulation and implementation during the endgame.
Does the opportunity focus on academic research or decision support?
The description emphasizes decision support. The modeling is expected to result in usable guidance that can be incorporated into real-world planning and policy discussions, not only academic modeling outputs.
What policy topics are specifically mentioned?
The opportunity specifically mentions endgame strategies such as managing outbreak risk, selecting immunization approaches, and planning for oral polio vaccine (OPV) cessation.
Why is OPV cessation an emphasis area?
OPV cessation is highlighted because it involves balancing the benefits of stopping OPV use against risks such as vaccine-derived poliovirus emergence and potential outbreaks. The opportunity stresses rigorous, integrated assessments that include epidemiology, strategy options, and resource implications.
What is a key deliverable related to surveillance?
A highlighted deliverable is a proposed surveillance decision support tool intended to help GPEI and countries use resources more carefully and strategically.
What decisions is the surveillance decision support tool expected to support?
Based on the description, the tool would support decisions tied to surveillance intensity and design, vaccination policy choices, and planning timelines.
What is the broader goal of the surveillance decision support tool?
The broader goal is to improve program efficiency while protecting progress toward eradication by enabling more strategic use of resources.
What is the CFDA number and program area listed?
The opportunity is categorized under health activity with CFDA 93.318.
Who is eligible to apply?
Eligibility is listed as "Others" in the opportunity summary provided.
How many awards were expected?
The opportunity anticipated a single award (Expected Awards: 1).
When was the opportunity created and what was the original closing date?
The creation date is listed as 2015-11-18, and the original closing date is listed as 2016-12-30.
Is there an award ceiling listed?
The source text shows an award ceiling of 0, and the summary as provided does not state a maximum award amount. In context, that typically suggests the ceiling amount was not specified in the extract provided rather than indicating there is no funding.
What makes this opportunity different from general infectious disease modeling efforts?
This opportunity is framed around a specific, integrated dynamic global polio model that links transmission dynamics with intervention strategies and the downstream risk and cost implications, with the explicit aim of producing practical decision support for GPEI partners, SAGE, and countries during the endgame.
What is the overall intent of the opportunity in one sentence?
To strengthen global polio eradication planning by using specialized, integrated modeling to inform policy-relevant decisions and tools that help decision-makers weigh tradeoffs among interventions, risks, and costs in the final stages of eradication.
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