Opportunity Information: Apply for MP CPI 23 003
The National Lupus Outreach and Clinical Trial Education Program is a discretionary grant opportunity from the U.S. Department of Health and Human Services (HHS), administered through the Office of Minority Health (OMH) within the Office of the Assistant Secretary for Health. The program is designed to fund practical, real-world projects that can show measurable success in increasing both enrollment and retention of racial and ethnic minority participants in lupus-related clinical trials. The underlying goal is not only to improve representation in research, but to help reduce persistent lupus-related health disparities that disproportionately affect minority communities.
A central reason for this initiative is the mismatch between who is most affected by lupus and who is typically represented in lupus clinical trials. The opportunity highlights that Black women are about three times more likely to develop lupus than White women, and that Hispanic, Asian, and Native American populations also face elevated risk. At the same time, the data cited in the announcement shows that African Americans account for roughly 43 percent of lupus cases, yet only about 14 percent of participants in lupus clinical trials. OMH frames this as a serious equity and scientific validity issue: when trials do not include the populations most impacted by a disease, treatments and medications may not perform as well across the full patient population, and important differences in effectiveness or safety can be missed.
Funded projects are expected to focus on interventions that directly address barriers to minority participation in lupus clinical trials. That includes outreach and education approaches that build awareness of clinical trials, strengthen trust, clarify what participation involves, and help potential participants navigate common logistical challenges. The program also places emphasis on retention, meaning awardees should not only recruit participants but also help them stay engaged through the full course of a study. OMH is looking for interventions that can be sustained over time, not one-off campaigns, and that can be strengthened through public-private collaborations and community partnerships. In practice, this often points to strategies such as partnering with community-based organizations, faith-based networks, lupus patient advocacy groups, local health systems, academic medical centers, and industry or research sponsors in ways that align incentives and reduce participation friction.
Another major expectation is that recipients will evaluate what they do and share what they learn. Awardees must implement both process and outcomes evaluation, which means documenting how the intervention was delivered (process) and measuring what changed as a result (outcomes), such as increases in minority enrollment rates, improved retention, higher levels of clinical trial knowledge, or reduced reported barriers to participation. OMH also expects dissemination of findings to diverse stakeholders, indicating that the work should be communicated in accessible ways to communities, researchers, health care providers, and decision-makers so effective models can be adopted more broadly.
The opportunity (Funding Opportunity Number MP CPI 23 003) supports projects under the health funding activity category and is associated with CFDA 93.137. The maximum award amount listed is $500,000, and OMH anticipated making about six awards. Eligible applicants are broad and include state, county, and local governments; special districts; independent school districts; public and state-controlled colleges and universities; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; and nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education). The opportunity was created on June 16, 2023, with an original application deadline of August 1, 2023, and applications were required to be submitted electronically by 6:00 pm Eastern Time.
Overall, the grant is aimed at building and proving effective, sustainable outreach and education models that increase minority participation in lupus clinical trials, strengthen the relevance and fairness of lupus research, and contribute to long-term reductions in lupus disparities affecting communities that bear a disproportionate share of the disease burden.Apply for MP CPI 23 003
- The Department of Health and Human Services, Office of the Assistant Secretary for Health in the health sector is offering a public funding opportunity titled "National Lupus Outreach and Clinical Trial Education Program" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.137.
- This funding opportunity was created on Jun 16, 2023.
- Applicants must submit their applications by Aug 01, 2023 Applications must be submitted electronically no later than 600 pm Eastern Time.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education.
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